SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549


SCHEDULE 13G/A


UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)*


Larimar Therapeutics, Inc.

(Name of Issuer)


Common Stock, par value $0.001 per share

(Title of Class of Securities)


517125100

(CUSIP Number)


12/31/2025

(Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
   Rule 13d-1(b)
   Rule 13d-1(c)
   Rule 13d-1(d)






SCHEDULE 13G/A
CUSIP No.
517125100


1 Names of Reporting Persons

RA Capital Management, L.P.
2 Check the appropriate box if a member of a Group (see instructions)

  (a)
  (b)
3SEC Use Only
4 Citizenship or Place of Organization

DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5 Sole Voting Power: 0.00
6 Shared Voting Power: 0.00
7 Sole Dispositive Power: 0.00
8 Shared Dispositive Power: 0.00
9 Aggregate Amount Beneficially Owned by Each Reporting Person

0.00
10 Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11 Percent of class represented by amount in row (9)

0.0 %
12 Type of Reporting Person (See Instructions)

IA, PN



SCHEDULE 13G/A
CUSIP No.
517125100


1 Names of Reporting Persons

Peter Kolchinsky
2 Check the appropriate box if a member of a Group (see instructions)

  (a)
  (b)
3SEC Use Only
4 Citizenship or Place of Organization

UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5 Sole Voting Power: 0.00
6 Shared Voting Power: 0.00
7 Sole Dispositive Power: 0.00
8 Shared Dispositive Power: 0.00
9 Aggregate Amount Beneficially Owned by Each Reporting Person

0.00
10 Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11 Percent of class represented by amount in row (9)

0.0 %
12 Type of Reporting Person (See Instructions)

HC, IN



SCHEDULE 13G/A
CUSIP No.
517125100


1 Names of Reporting Persons

Rajeev Shah
2 Check the appropriate box if a member of a Group (see instructions)

  (a)
  (b)
3SEC Use Only
4 Citizenship or Place of Organization

UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5 Sole Voting Power: 0.00
6 Shared Voting Power: 0.00
7 Sole Dispositive Power: 0.00
8 Shared Dispositive Power: 0.00
9 Aggregate Amount Beneficially Owned by Each Reporting Person

0.00
10 Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11 Percent of class represented by amount in row (9)

0.0 %
12 Type of Reporting Person (See Instructions)

HC, IN



SCHEDULE 13G/A
CUSIP No.
517125100


1 Names of Reporting Persons

RA Capital Healthcare Fund, L.P.
2 Check the appropriate box if a member of a Group (see instructions)

  (a)
  (b)
3SEC Use Only
4 Citizenship or Place of Organization

DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5 Sole Voting Power: 0.00
6 Shared Voting Power: 0.00
7 Sole Dispositive Power: 0.00
8 Shared Dispositive Power: 0.00
9 Aggregate Amount Beneficially Owned by Each Reporting Person

0.00
10 Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11 Percent of class represented by amount in row (9)

0.0 %
12 Type of Reporting Person (See Instructions)

PN




SCHEDULE 13G/A

Item 1. 
(a) Name of issuer:

Larimar Therapeutics, Inc.
(b) Address of issuer's principal executive offices:

Three Bala Plaza East, Suite 506, Bala Cynwyd, PA, 19004.
Item 2. 
(a) Name of person filing:

The names of the persons filing this report (collectively, the "Reporting Persons") are: RA Capital Management, L.P. ("RA Capital") Peter Kolchinsky Rajeev Shah RA Capital Healthcare Fund, L.P. (the "Fund") The Reporting Persons expressly disclaim status as a "group" for purposes of this Schedule 13G.
(b) Address or principal business office or, if none, residence:

The address of the principal business office of each of the Reporting Persons is: c/o RA Capital Management, L.P., 200 Berkeley Street, 18th Floor, Boston MA 02116
(c) Citizenship:

RA Capital and the Fund are Delaware limited partnerships. Dr. Kolchinsky and Mr. Shah are United States citizens.
(d) Title of class of securities:

Common Stock, par value $0.001 per share
(e) CUSIP No.:

517125100
Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
       please specify the type of institution:
(k)   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
 
Item 4.Ownership
(a) Amount beneficially owned:

Row 9 of each Reporting Person's cover page to this Schedule 13G sets forth the aggregate number of securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.
(b) Percent of class:

Row 11 of each Reporting Person's cover page to this Schedule 13G sets forth the percentages of the securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.   %
(c) Number of shares as to which the person has:
  (i) Sole power to vote or to direct the vote:

Row 5 of each Reporting Person's cover page to this Schedule 13G sets forth the sole power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.

  (ii) Shared power to vote or to direct the vote:

Row 6 of each Reporting Person's cover page to this Schedule 13G sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.

  (iii) Sole power to dispose or to direct the disposition of:

Row 7 of each Reporting Person's cover page to this Schedule 13G sets forth the sole power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.

  (iv) Shared power to dispose or to direct the disposition of:

Row 8 of each Reporting Person's cover page to this Schedule 13G sets forth the shared power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of December 31, 2025 and is incorporated by reference.

Item 5.Ownership of 5 Percent or Less of a Class.
 
   Ownership of 5 percent or less of a class
Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
 
Not Applicable
Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
 
Not Applicable
Item 8.Identification and Classification of Members of the Group.
 
Not Applicable
Item 9.Notice of Dissolution of Group.
 
Not Applicable

Item 10.Certifications:
 
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

    SIGNATURE 
 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 
RA Capital Management, L.P.
 Signature:/s/ Peter Kolchinsky
 Name/Title:By Peter Kolchinsky, Authorized Signatory
 Date:02/17/2026
 
Peter Kolchinsky
 Signature:/s/ Peter Kolchinsky
 Name/Title:Peter Kolchinsky
 Date:02/17/2026
 
Rajeev Shah
 Signature:/s/ Rajeev Shah
 Name/Title:Rajeev Shah
 Date:02/17/2026
 
RA Capital Healthcare Fund, L.P.
 Signature:/s/ Peter Kolchinsky
 Name/Title:By RA Capital Healthcare Fund GP, LLC, its General Partner, By Peter Kolchinsky, Manager
 Date:02/17/2026
Exhibit Information: Exhibit 99.1 Joint Filing Agreement (incorporated by reference to Exhibit 1 to Schedule 13G filed on February 26, 2024)