Russia launched a large-scale invasion of
Ukraine on February 24, 2022. The extent and duration of the military action, resulting sanctions and
resulting future market disruptions, including declines in its stock markets and the value of the ruble against the U.S. dollar, are impossible to predict, but could be significant. Disruptions caused by Russian military action or other
actions (including cyberattacks and espionage) or resulting actual and threatened responses to such
activity, including purchasing and financing restrictions, boycotts or changes in consumer or purchaser
preferences, sanctions, import and export restrictions, tariffs or cyberattacks on the Russian government, Russian companies, or Russian individuals, including politicians, may impact Russia’s economy and Russian companies in
which the Fund invests. Actual and threatened responses to Russian military action may also impact the
markets for certain Russian commodities, such as oil and natural gas, as well as other sectors of the
Russian economy, and are likely to have collateral impacts on such sectors globally. Russian companies may be unable to pay dividends and, if they pay dividends, the Fund may be unable to receive them. As a result of sanctions, the Fund is
currently restricted from trading in Russian securities, including those in its portfolio, and the
Underlying Index has removed Russian securities. It is unknown when, or if, sanctions may be lifted or the
Fund’s ability to trade in Russian securities will resume.
Risk of Investing in the U.S. Investing in U.S. issuers subjects the Fund to legal, regulatory, political, currency, security, and economic risks that are specific to the U.S. Certain changes in the U.S., such as a weakening of the U.S. economy or a
decline in its financial markets, may have an adverse effect on U.S. issuers.
Securities Lending Risk. The Fund may engage in
securities lending. Securities lending involves the risk that the Fund may lose money because the borrower
of the loaned securities fails to return the securities in a timely manner or at all. The Fund could also
lose money in the event of a decline in the value of collateral provided for loaned securities or a decline in the value of any investments made with cash collateral. These events could also trigger adverse tax consequences for the
Fund.
Tracking Error Risk. The Fund may be subject to
“tracking error,” which is the divergence of the Fund’s performance from that of the Underlying Index. Tracking error may occur due to a number of factors, including differences between the securities
and other assets held in the Fund’s portfolio and those included in the Underlying Index; differences
in the timing and methodologies used to value securities and other assets; transaction costs and other
expenses incurred by the Fund that the Underlying Index does not incur; the Fund’s holding of uninvested cash; differences in the timing of the accrual or the valuation of dividends or interest received by the Fund or distributions paid to
Fund shareholders; tax gains or losses; the requirements for the Fund to maintain pass-through tax
treatment; portfolio transactions
carried out to minimize the distribution of capital gains to shareholders; the acceptance of custom baskets; changes to
the Underlying Index; and impacts to the Fund of complying with certain regulatory requirements or limits.
Tracking error risk may be heightened during times of increased market volatility or other unusual market
conditions.
U.S. Agency Mortgage-Backed
Securities Risk. MBS represent interests in “pools” of mortgages and are subject to interest rate, prepayment, and extension risk. MBS may be issued or guaranteed by the U.S. government or one of its agencies or sponsored entities. Some MBS may not be backed by the full
faith and credit of the U.S. government and thus represent greater credit risk. MBS react differently than
other bonds to changes in interest rates due to prepayment and extension risks. Small movements in interest
rates (both increases and decreases) may quickly and significantly reduce the value of certain MBS. MBS
prices may reflect adverse economic and market conditions. MBS are subject to the risk of default on the
underlying mortgage loans, particularly during periods of economic downturn. The default or bankruptcy of a
counterparty to a TBA transaction would expose the Fund to possible losses.
U.S. Treasury Obligations Risk. U.S. Treasury
obligations may differ from other securities in their interest rates, maturities, times of issuance and
other characteristics and may provide relatively lower returns than those of other securities. Changes in
the U.S. government’s financial condition or credit rating may cause the value of U.S. Treasury
obligations to decline. Direct obligations of the U.S. Treasury have historically involved little risk of
loss of principal if held to maturity, but the market value of such securities is not guaranteed and may fluctuate. Although U.S. Treasury obligations are backed by the full faith and credit of the United States, circumstances could arise that could
prevent the timely payment of interest or principal.
Valuation Risk. The price that the Fund could receive upon the sale (or other disposition) of a security or other asset may differ
from the Fund’s valuation of the security or other asset, particularly for securities or other assets
that trade in low volume or volatile markets or that are valued using a fair value methodology. The price
received by the Fund also may differ from the value used by the Underlying Index. In addition, the value of
the securities or other assets in the Fund’s portfolio may change on days or during time periods when
investors are not able to purchase or sell Fund shares. Authorized Participants that create or redeem Fund
shares on days when the Fund is holding fair-valued securities or other assets may receive fewer or more
shares, or lower or higher redemption proceeds, than they would have received had the securities or other
assets not been fair valued or been valued using a different methodology. The ability to value investments
may be impacted by technological issues or errors by pricing services or other third-party service providers.